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Single-dose Ag85B-ESAT6–loaded poly(lactic-co-glycolic acid) nanoparticles confer protective immunity against tuberculosis

BACKGROUND: Bacillus Calmette–Guérin, the attenuated strain of Mycobacterium bovis, remains the only available vaccine against tuberculosis (TB). However, its ineffectiveness in adults against pulmonary TB and varied protective efficacy (0–80%) speak to an urgent need for the development of an impro...

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Detalles Bibliográficos
Autores principales:	Malik, Anshu, Gupta, Manish, Mani, Rajesh, Bhatnagar, Rakesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501725/ https://www.ncbi.nlm.nih.gov/pubmed/31118627 http://dx.doi.org/10.2147/IJN.S172391

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