Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes

We describe a case of a 37-year-old female, indicated for in vitro fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband's blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes,...

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Autores principales: Araújo Filho, Edilberto, Fácio, Cássio Leão, Machado-Paula, Ligiane Alves, de Oliveira, Mariana Angelozzi, Martinhago, Ciro Dresch, Araújo, Leonardo Previato, Araújo, Lígia Fernanda P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501749/
https://www.ncbi.nlm.nih.gov/pubmed/30614664
http://dx.doi.org/10.5935/1518-0557.20180081
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author Araújo Filho, Edilberto
Fácio, Cássio Leão
Machado-Paula, Ligiane Alves
de Oliveira, Mariana Angelozzi
Martinhago, Ciro Dresch
Araújo, Leonardo Previato
Araújo, Lígia Fernanda P.
author_facet Araújo Filho, Edilberto
Fácio, Cássio Leão
Machado-Paula, Ligiane Alves
de Oliveira, Mariana Angelozzi
Martinhago, Ciro Dresch
Araújo, Leonardo Previato
Araújo, Lígia Fernanda P.
author_sort Araújo Filho, Edilberto
collection PubMed
description We describe a case of a 37-year-old female, indicated for in vitro fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband's blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes, follicular fluid, and cumulus cells. RT-PCR results for the follicular fluid and cumulus cells were negative for ZIKV, and positive for only 2 oocytes. This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes, and will contribute to the understanding of ZIKV infection and transmission.
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spelling pubmed-65017492019-05-20 Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes Araújo Filho, Edilberto Fácio, Cássio Leão Machado-Paula, Ligiane Alves de Oliveira, Mariana Angelozzi Martinhago, Ciro Dresch Araújo, Leonardo Previato Araújo, Lígia Fernanda P. JBRA Assist Reprod Case Report We describe a case of a 37-year-old female, indicated for in vitro fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband's blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes, follicular fluid, and cumulus cells. RT-PCR results for the follicular fluid and cumulus cells were negative for ZIKV, and positive for only 2 oocytes. This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes, and will contribute to the understanding of ZIKV infection and transmission. Brazilian Society of Assisted Reproduction 2019 /pmc/articles/PMC6501749/ /pubmed/30614664 http://dx.doi.org/10.5935/1518-0557.20180081 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Araújo Filho, Edilberto
Fácio, Cássio Leão
Machado-Paula, Ligiane Alves
de Oliveira, Mariana Angelozzi
Martinhago, Ciro Dresch
Araújo, Leonardo Previato
Araújo, Lígia Fernanda P.
Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
title Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
title_full Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
title_fullStr Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
title_full_unstemmed Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
title_short Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
title_sort case report of zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501749/
https://www.ncbi.nlm.nih.gov/pubmed/30614664
http://dx.doi.org/10.5935/1518-0557.20180081
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