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Significant Strain Variation in the Mutation Spectra of Inbred Laboratory Mice
Mutation provides the ultimate source of all new alleles in populations, including variants that cause disease and fuel adaptation. Recent whole genome sequencing studies have uncovered variation in the mutation rate among individuals and differences in the relative frequency of specific nucleotide...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501876/ https://www.ncbi.nlm.nih.gov/pubmed/30753674 http://dx.doi.org/10.1093/molbev/msz026 |