Protocol for a controlled human infection with genetically modified Neisseria lactamica expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine

INTRODUCTION: Neisseria lactamica is a commensal organism found in the human nasopharynx and is closely related to the pathogen N. meningitidis (meningococcus). Carriage of N. lactamica is associated with reduced meningococcal carriage and disease. We summarise an ethically approved protocol for an...

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Detalles Bibliográficos
Autores principales: Gbesemete, Diane, Laver, Jay Robert, de Graaf, Hans, Ibrahim, Muktar, Vaughan, Andrew, Faust, Saul, Gorringe, Andrew, Read, Robert Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501966/
https://www.ncbi.nlm.nih.gov/pubmed/31048443
http://dx.doi.org/10.1136/bmjopen-2018-026544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501966/
https://www.ncbi.nlm.nih.gov/pubmed/31048443
http://dx.doi.org/10.1136/bmjopen-2018-026544

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