Cargando…

Counterintuitive results from observational data: a case study and discussion

OBJECTIVE: To explore the issue of counterintuitive data via analysis of a representative case in which the data obtained was unexpected and inconsistent with current knowledge. We then discuss the issue of counterintuitive data while developing a framework for approaching such findings. DESIGN: The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doty, Erik, Stone, David J, McCague, Ned, Celi, Leo Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Intensive Care
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502001/ https://www.ncbi.nlm.nih.gov/pubmed/31061037 http://dx.doi.org/10.1136/bmjopen-2018-026447

Ejemplares similares

Interrogating a clinical database to study treatment of hypotension in the critically ill
por: Lee, Joon, et al.
Publicado: (2012)

Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis)
por: Scott, Jonathan, et al.
Publicado: (2022)

Effectiveness of a sepsis programme in a resource-limited setting: a retrospective analysis of data of a prospective observational study (Ubon-sepsis)
por: Booraphun, Suchart, et al.
Publicado: (2021)

Multicentre observational status-epilepticus registry: protocol for ICTAL
por: Jacq, Gwenaelle, et al.
Publicado: (2022)

Observational study of the effects of traumatic injury, haemorrhagic shock and resuscitation on the microcirculation: a protocol for the MICROSHOCK study
por: Hutchings, Sam, et al.
Publicado: (2016)

Validation and optimisation of an ICD-10-coded case definition for sepsis using administrative health data
por: Jolley, Rachel J, et al.
Publicado: (2015)

Study protocol and pilot results of an observational cohort study evaluating effect of red blood cell transfusion on oxygenation and mitochondrial oxygen tension in critically ill patients with anaemia: the INsufficient Oxygenation in the Intensive Care Unit (INOX ICU-2) study
por: Baysan, Meryem, et al.
Publicado: (2020)

Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data
por: Annane, Djillali, et al.
Publicado: (2020)

Study protocol for COVID-RV: a multicentre prospective observational cohort study of right ventricular dysfunction in ventilated patients with COVID-19
por: Willder, Jennifer Mary, et al.
Publicado: (2021)

Variation in the practice of discontinuing mechanical ventilation in critically ill adults: study protocol for an international prospective observational study
por: Burns, Karen E A, et al.
Publicado: (2019)

Design and rationale of the COVID-19 Critical Care Consortium international, multicentre, observational study
por: Li Bassi, Gianluigi, et al.
Publicado: (2020)

Mid-German Sepsis Cohort (MSC): a prospective observational study of sepsis survivorship
por: Fleischmann-Struzek, Carolin, et al.
Publicado: (2021)

Multicentre observational study on practice of ventilation in brain injured patients: the VENTIBRAIN study protocol
por: Robba, Chiara, et al.
Publicado: (2021)

Response to physical rehabilitation and recovery trajectories following critical illness: individual participant data meta-analysis protocol
por: Jones, Jennifer R A, et al.
Publicado: (2020)

Research protocol for platelets in out-of-hospital cardiac arrest: an observational, case-controlled, feasibility study to assess coagulation and platelet function abnormalities with ROTEM following out-of-hospital cardiac arrest (PoHCAR)
por: Skorko, Agnieszka, et al.
Publicado: (2017)

The efficacy of activated protein C for the treatment of sepsis: incorporating observational evidence with a Bayesian approach
por: Zhang, Zhongheng
Publicado: (2015)

Multicentre, longitudinal, observational cohort study to examine the relationship between neutrophil function and sepsis in adults and children with severe thermal injuries: a protocol for the Scientific Investigation of the Biological Pathways Following Thermal Injury-2 (SIFTI-2) study
por: Hazeldine, Jon, et al.
Publicado: (2021)

International prospective observational study on intracranial pressure in intensive care (ICU): the SYNAPSE-ICU study protocol
por: Citerio, Giuseppe, et al.
Publicado: (2019)

Levosimendan and Global Longitudinal Strain Assessment in Sepsis (GLASSES 1): a study protocol for an observational study
por: Cappellini, Iacopo, et al.
Publicado: (2020)

Association between minimal decrease in platelet counts and outcomes in septic patients: a retrospective observational study
por: Liu, Xing, et al.
Publicado: (2023)

Assessing the relationship between near-infrared spectroscopy-derived regional cerebral oxygenation and neurological dysfunction in critically ill adults: a prospective observational multicentre protocol, on behalf of the Canadian Critical Care Trials Group
por: Wood, Michael D, et al.
Publicado: (2019)

Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors
por: D’Aragon, Frederick, et al.
Publicado: (2017)

Resource use, characteristics and outcomes of prolonged non-invasive ventilation: a single-centre observational study in China
por: Duan, Jun, et al.
Publicado: (2018)

Premedication practices for tracheal intubation in neonates transported by French medical transport teams: a prospective observational study
por: Carbajal, Ricardo, et al.
Publicado: (2019)

Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill patients (HEMICU): a prospective observational study protocol
por: Lachmann, Gunnar, et al.
Publicado: (2019)

Inter-rater reliability and prognostic value of baseline Radiographic Assessment of Lung Edema (RALE) scores in observational cohort studies of inpatients with COVID-19
por: Al-Yousif, Nameer, et al.
Publicado: (2023)

Butyrylcholinesterase as a perioperative complication marker in patients after transcatheter aortic valve implantation: a prospective observational study
por: Michels, Bernhard, et al.
Publicado: (2021)

Protocol for a prospective observational study on the association of variables obtained by contrast-enhanced ultrasonography and sepsis-associated acute kidney injury
por: Liu, Ning, et al.
Publicado: (2019)

The intermediate care unit as a cost-reducing critical care facility in tertiary referral hospitals: a single-centre observational study
por: Plate, Joost D J, et al.
Publicado: (2019)

Dose–response association between fluid overload and in-hospital mortality in critically ill patients: a multicentre, prospective, observational cohort study
por: Wang, Meiping, et al.
Publicado: (2020)

Chinesisation, adaptation and validation of the Chelsea Critical Care Physical Assessment Tool in critically ill patients: a cross-sectional observational study
por: Zhang, Zhigang, et al.
Publicado: (2021)

Chest radiography for simplified evaluation of central venous catheter tip positioning for safe and accurate haemodynamic monitoring: a retrospective observational study
por: Kang, Minwoo, et al.
Publicado: (2021)

Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study
por: Chaiwat, Onuma, et al.
Publicado: (2022)

Prospective longitudinal observational study of the macro and micro haemodynamic responses to septic shock in the renal and systemic circulations: a protocol for the MICROSHOCK – RENAL study
por: Watchorn, Jim, et al.
Publicado: (2019)

Early prediction of in-hospital mortality in acute pancreatitis: a retrospective observational cohort study based on a large multicentre critical care database
por: Li, Caifeng, et al.
Publicado: (2020)

Critical illness myopathy and trajectory of recovery in acute kidney injury requiring continuous renal replacement therapy: a prospective observational trial protocol
por: Teixeira, J Pedro, et al.
Publicado: (2023)

Primary bacteraemia is associated with a higher mortality risk compared with pulmonary and intra-abdominal infections in patients with sepsis: a prospective observational cohort study
por: Mansur, Ashham, et al.
Publicado: (2015)

Feasibility of implementing Extubation Advisor, a clinical decision support tool to improve extubation decision-making in the ICU: a mixed-methods observational study
por: Sarti, Aimee J, et al.
Publicado: (2021)

Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study
por: Oddo, Mauro, et al.
Publicado: (2021)

Towards a decision support tool for intensive care discharge: machine learning algorithm development using electronic healthcare data from MIMIC-III and Bristol, UK
por: McWilliams, Christopher J, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9s9t41e7p77jakv1v071ipo0j1