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Cough, a vital reflex. Mechanisms, determinants and measurements

Cough is a natural defense mechanism that protects the respiratory tract from inhaling foreign bodies and by clearing excessive bronchial secretions. As a spontaneous reflex arc, it involves receptors, an afferent pathway, a center processing information, an efferent pathway and effectors. The deter...

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Autores principales: Francesco, Andrani, Marina, Aiello, Giuseppina, Bertorelli, Ernesto, Crisafulli, Alfredo, Chetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502102/
https://www.ncbi.nlm.nih.gov/pubmed/30657115
http://dx.doi.org/10.23750/abm.v89i4.6182
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author Francesco, Andrani
Marina, Aiello
Giuseppina, Bertorelli
Ernesto, Crisafulli
Alfredo, Chetta
author_facet Francesco, Andrani
Marina, Aiello
Giuseppina, Bertorelli
Ernesto, Crisafulli
Alfredo, Chetta
author_sort Francesco, Andrani
collection PubMed
description Cough is a natural defense mechanism that protects the respiratory tract from inhaling foreign bodies and by clearing excessive bronchial secretions. As a spontaneous reflex arc, it involves receptors, an afferent pathway, a center processing information, an efferent pathway and effectors. The determinant factor of cough efficacy is the operational volume of the lung, which in turn relies on the strength and coordination of respiratory and laryngeal muscles as well as on lung mechanics. Respiratory muscle weakness and dysfunction as well as expiratory flow limitation and lung hyperinflation may occur in some neuromuscular disorders and in obstructive airway diseases, respectively. Accordingly, all these diseases may show an ineffective cough. In this brief overview, we deal with the determinants of the cough efficacy and the clinical conditions affecting cough efficacy as well as the cough’s efficacy measurements in clinical setting. (www.actabiomedica.it)
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spelling pubmed-65021022019-05-08 Cough, a vital reflex. Mechanisms, determinants and measurements Francesco, Andrani Marina, Aiello Giuseppina, Bertorelli Ernesto, Crisafulli Alfredo, Chetta Acta Biomed Focus on Cough is a natural defense mechanism that protects the respiratory tract from inhaling foreign bodies and by clearing excessive bronchial secretions. As a spontaneous reflex arc, it involves receptors, an afferent pathway, a center processing information, an efferent pathway and effectors. The determinant factor of cough efficacy is the operational volume of the lung, which in turn relies on the strength and coordination of respiratory and laryngeal muscles as well as on lung mechanics. Respiratory muscle weakness and dysfunction as well as expiratory flow limitation and lung hyperinflation may occur in some neuromuscular disorders and in obstructive airway diseases, respectively. Accordingly, all these diseases may show an ineffective cough. In this brief overview, we deal with the determinants of the cough efficacy and the clinical conditions affecting cough efficacy as well as the cough’s efficacy measurements in clinical setting. (www.actabiomedica.it) Mattioli 1885 2018 /pmc/articles/PMC6502102/ /pubmed/30657115 http://dx.doi.org/10.23750/abm.v89i4.6182 Text en Copyright: © 2018 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Focus on
Francesco, Andrani
Marina, Aiello
Giuseppina, Bertorelli
Ernesto, Crisafulli
Alfredo, Chetta
Cough, a vital reflex. Mechanisms, determinants and measurements
title Cough, a vital reflex. Mechanisms, determinants and measurements
title_full Cough, a vital reflex. Mechanisms, determinants and measurements
title_fullStr Cough, a vital reflex. Mechanisms, determinants and measurements
title_full_unstemmed Cough, a vital reflex. Mechanisms, determinants and measurements
title_short Cough, a vital reflex. Mechanisms, determinants and measurements
title_sort cough, a vital reflex. mechanisms, determinants and measurements
topic Focus on
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502102/
https://www.ncbi.nlm.nih.gov/pubmed/30657115
http://dx.doi.org/10.23750/abm.v89i4.6182
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