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Epidemiology and risk factors of pancreatic cancer

The most frequent pancreatic cancer is pancreatic adenocarcinoma. It has high and early locally and distant invasiveness; this is the reason why it often shows little sign or symptoms in early stage and poor prognosis after the diagnosis, frequently in advanced stage. Although it is possible to dete...

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Autores principales: Mario, Capasso, Marilisa, Franceschi, Kryssia, Isabel Rodriguez-Castro, Pellegrino, Crafa, Ginevra, Cambiè, Chiara, Miraglia, Alberto, Barchi, Antonio, Nouvenne, Gioacchino, Leandro, Tiziana, Meschi, Gian, Luigi de’ Angelis, Francesco, Di Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502190/
https://www.ncbi.nlm.nih.gov/pubmed/30561407
http://dx.doi.org/10.23750/abm.v89i9-S.7923
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author Mario, Capasso
Marilisa, Franceschi
Kryssia, Isabel Rodriguez-Castro
Pellegrino, Crafa
Ginevra, Cambiè
Chiara, Miraglia
Alberto, Barchi
Antonio, Nouvenne
Gioacchino, Leandro
Tiziana, Meschi
Gian, Luigi de’ Angelis
Francesco, Di Mario
author_facet Mario, Capasso
Marilisa, Franceschi
Kryssia, Isabel Rodriguez-Castro
Pellegrino, Crafa
Ginevra, Cambiè
Chiara, Miraglia
Alberto, Barchi
Antonio, Nouvenne
Gioacchino, Leandro
Tiziana, Meschi
Gian, Luigi de’ Angelis
Francesco, Di Mario
author_sort Mario, Capasso
collection PubMed
description The most frequent pancreatic cancer is pancreatic adenocarcinoma. It has high and early locally and distant invasiveness; this is the reason why it often shows little sign or symptoms in early stage and poor prognosis after the diagnosis, frequently in advanced stage. Although it is possible to detect this tumor in early stage because of its neoplastic precursor (PanINs). Epidemiological data shows that pancreatic cancer is not very common but obvious it is one of the most neoplastic death-cause in the world. The trend of incidence is quite increasing through years, proportionally to the increase of risk factors. About risk factors, it is not easy to detect in all the cases but it is known the role of some of that: there are hereditary risk factors, such as genetic pattern like HBOC, HNPCC, FAP, PJS, FAMMM, HP and CF and environmental ones (modifiable) such as smoke, alcohol consumption, chronic pancreatitis, obesity and diabetes mellitus. This narrative review aims to analyze the epidemiological data of pancreatic cancer and associated risk factors. (www.actabiomedica.it)
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spelling pubmed-65021902019-05-08 Epidemiology and risk factors of pancreatic cancer Mario, Capasso Marilisa, Franceschi Kryssia, Isabel Rodriguez-Castro Pellegrino, Crafa Ginevra, Cambiè Chiara, Miraglia Alberto, Barchi Antonio, Nouvenne Gioacchino, Leandro Tiziana, Meschi Gian, Luigi de’ Angelis Francesco, Di Mario Acta Biomed Review The most frequent pancreatic cancer is pancreatic adenocarcinoma. It has high and early locally and distant invasiveness; this is the reason why it often shows little sign or symptoms in early stage and poor prognosis after the diagnosis, frequently in advanced stage. Although it is possible to detect this tumor in early stage because of its neoplastic precursor (PanINs). Epidemiological data shows that pancreatic cancer is not very common but obvious it is one of the most neoplastic death-cause in the world. The trend of incidence is quite increasing through years, proportionally to the increase of risk factors. About risk factors, it is not easy to detect in all the cases but it is known the role of some of that: there are hereditary risk factors, such as genetic pattern like HBOC, HNPCC, FAP, PJS, FAMMM, HP and CF and environmental ones (modifiable) such as smoke, alcohol consumption, chronic pancreatitis, obesity and diabetes mellitus. This narrative review aims to analyze the epidemiological data of pancreatic cancer and associated risk factors. (www.actabiomedica.it) Mattioli 1885 2018 /pmc/articles/PMC6502190/ /pubmed/30561407 http://dx.doi.org/10.23750/abm.v89i9-S.7923 Text en Copyright: © 2018 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Review
Mario, Capasso
Marilisa, Franceschi
Kryssia, Isabel Rodriguez-Castro
Pellegrino, Crafa
Ginevra, Cambiè
Chiara, Miraglia
Alberto, Barchi
Antonio, Nouvenne
Gioacchino, Leandro
Tiziana, Meschi
Gian, Luigi de’ Angelis
Francesco, Di Mario
Epidemiology and risk factors of pancreatic cancer
title Epidemiology and risk factors of pancreatic cancer
title_full Epidemiology and risk factors of pancreatic cancer
title_fullStr Epidemiology and risk factors of pancreatic cancer
title_full_unstemmed Epidemiology and risk factors of pancreatic cancer
title_short Epidemiology and risk factors of pancreatic cancer
title_sort epidemiology and risk factors of pancreatic cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502190/
https://www.ncbi.nlm.nih.gov/pubmed/30561407
http://dx.doi.org/10.23750/abm.v89i9-S.7923
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