p62-mediated Selective autophagy endows virus-transformed cells with insusceptibility to DNA damage under oxidative stress

DNA damage response (DDR) and selective autophagy both can be activated by reactive oxygen/nitrogen species (ROS/RNS), and both are of paramount importance in cancer development. The selective autophagy receptor and ubiquitin (Ub) sensor p62 plays a key role in their crosstalk. ROS production has be...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Howell, Mary E. A., Sparks-Wallace, Ayrianna, Hawkins, Caroline, Nicksic, Camri A., Kohne, Carissa, Hall, Kenton H., Moorman, Jonathan P., Yao, Zhi Q., Ning, Shunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502431/
https://www.ncbi.nlm.nih.gov/pubmed/31017975
http://dx.doi.org/10.1371/journal.ppat.1007541

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