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The arginine sensing and transport binding sites are distinct in the human pathogen Leishmania
The intracellular protozoan parasite Leishmania donovani causes human visceral leishmaniasis. Intracellular L. donovani that proliferate inside macrophage phagolysosomes compete with the host for arginine, creating a situation that endangers parasite survival. Parasites have a sensor that upon argin...
Autores principales: | Pawar, Harsh, Puri, Madhu, Fischer Weinberger, Renana, Madhubala, Rentala, Zilberstein, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502434/ https://www.ncbi.nlm.nih.gov/pubmed/31017889 http://dx.doi.org/10.1371/journal.pntd.0007304 |
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