A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women

To investigate the prebiotic effect of lactulose at low dosages, we assessed changes in defaecation frequency following ingestion of 1, 2, or 3 g/day of lactulose for 2 weeks. Each test was carried out after a 2-week washout period. This was an open-label, before-after trial that enrolled 26 healthy...

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Detalles Bibliográficos
Autores principales: SAKAI, Yohei, SEKI, Nobuo, HAMANO, Hirokazu, OCHI, Hiroshi, ABE, Fumiaki, SHIMIZU, Fumiko, MASUDA, Kazuya, IINO, Hisakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMFH Press 2018
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502711/
https://www.ncbi.nlm.nih.gov/pubmed/31106110
http://dx.doi.org/10.12938/bmfh.18-013
Descripción
Sumario:To investigate the prebiotic effect of lactulose at low dosages, we assessed changes in defaecation frequency following ingestion of 1, 2, or 3 g/day of lactulose for 2 weeks. Each test was carried out after a 2-week washout period. This was an open-label, before-after trial that enrolled 26 healthy Japanese women. The defaecation frequency, number of defaecation days, and number of faecal bifidobacteria increased significantly compared with before ingestion of 1, 2, and 3 g/day of lactulose. These results suggest that even 1 g/day of lactulose could have a prebiotic effect.

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