A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women

To investigate the prebiotic effect of lactulose at low dosages, we assessed changes in defaecation frequency following ingestion of 1, 2, or 3 g/day of lactulose for 2 weeks. Each test was carried out after a 2-week washout period. This was an open-label, before-after trial that enrolled 26 healthy...

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Autores principales: SAKAI, Yohei, SEKI, Nobuo, HAMANO, Hirokazu, OCHI, Hiroshi, ABE, Fumiaki, SHIMIZU, Fumiko, MASUDA, Kazuya, IINO, Hisakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMFH Press 2018
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502711/
https://www.ncbi.nlm.nih.gov/pubmed/31106110
http://dx.doi.org/10.12938/bmfh.18-013
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author SAKAI, Yohei
SEKI, Nobuo
HAMANO, Hirokazu
OCHI, Hiroshi
ABE, Fumiaki
SHIMIZU, Fumiko
MASUDA, Kazuya
IINO, Hisakazu
author_facet SAKAI, Yohei
SEKI, Nobuo
HAMANO, Hirokazu
OCHI, Hiroshi
ABE, Fumiaki
SHIMIZU, Fumiko
MASUDA, Kazuya
IINO, Hisakazu
author_sort SAKAI, Yohei
collection PubMed
description To investigate the prebiotic effect of lactulose at low dosages, we assessed changes in defaecation frequency following ingestion of 1, 2, or 3 g/day of lactulose for 2 weeks. Each test was carried out after a 2-week washout period. This was an open-label, before-after trial that enrolled 26 healthy Japanese women. The defaecation frequency, number of defaecation days, and number of faecal bifidobacteria increased significantly compared with before ingestion of 1, 2, and 3 g/day of lactulose. These results suggest that even 1 g/day of lactulose could have a prebiotic effect.
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spelling pubmed-65027112019-05-17 A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women SAKAI, Yohei SEKI, Nobuo HAMANO, Hirokazu OCHI, Hiroshi ABE, Fumiaki SHIMIZU, Fumiko MASUDA, Kazuya IINO, Hisakazu Biosci Microbiota Food Health Note To investigate the prebiotic effect of lactulose at low dosages, we assessed changes in defaecation frequency following ingestion of 1, 2, or 3 g/day of lactulose for 2 weeks. Each test was carried out after a 2-week washout period. This was an open-label, before-after trial that enrolled 26 healthy Japanese women. The defaecation frequency, number of defaecation days, and number of faecal bifidobacteria increased significantly compared with before ingestion of 1, 2, and 3 g/day of lactulose. These results suggest that even 1 g/day of lactulose could have a prebiotic effect. BMFH Press 2018-12-29 2019 /pmc/articles/PMC6502711/ /pubmed/31106110 http://dx.doi.org/10.12938/bmfh.18-013 Text en ©2019 BMFH Press This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Note
SAKAI, Yohei
SEKI, Nobuo
HAMANO, Hirokazu
OCHI, Hiroshi
ABE, Fumiaki
SHIMIZU, Fumiko
MASUDA, Kazuya
IINO, Hisakazu
A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women
title A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women
title_full A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women
title_fullStr A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women
title_full_unstemmed A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women
title_short A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women
title_sort study of the prebiotic effect of lactulose at low dosages in healthy japanese women
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502711/
https://www.ncbi.nlm.nih.gov/pubmed/31106110
http://dx.doi.org/10.12938/bmfh.18-013
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