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Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma
Current therapies for most non-infectious diseases are directed at or affect functionality of the human translated genome, barely 2% of all genetic information. By contrast, the therapeutic potential of targeting the transcriptome, ~ 70% of the genome, remains largely unexplored. RNA therapeutics is...
Autores principales: | Soriano, Aroa, Masanas, Marc, Boloix, Ariadna, Masiá, Núria, París-Coderch, Laia, Piskareva, Olga, Jiménez, Carlos, Henrich, Kai-Oliver, Roma, Josep, Westermann, Frank, Stallings, Raymond L., Sábado, Constantino, de Toledo, Josep Sánchez, Santamaria, Anna, Gallego, Soledad, Segura, Miguel F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502783/ https://www.ncbi.nlm.nih.gov/pubmed/30770954 http://dx.doi.org/10.1007/s00018-019-03041-4 |
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