Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy

Cystine-knot peptides are attractive templates in drug discovery due to a number of features they possess including their 3D conformation, physicochemical stability and synthetic tractability. Yet, their cellular uptake mechanisms remain largely unexplored. Recently, we demonstrated that the cystine...

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Detalles Bibliográficos
Autores principales: Gao, Xinxin, De Mazière, Ann, Iaea, David B., Arthur, Christopher P., Klumperman, Judith, Ciferri, Claudio, Hannoush, Rami N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502800/
https://www.ncbi.nlm.nih.gov/pubmed/31061420
http://dx.doi.org/10.1038/s41598-019-43285-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502800/
https://www.ncbi.nlm.nih.gov/pubmed/31061420
http://dx.doi.org/10.1038/s41598-019-43285-5

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