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Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy
Cystine-knot peptides are attractive templates in drug discovery due to a number of features they possess including their 3D conformation, physicochemical stability and synthetic tractability. Yet, their cellular uptake mechanisms remain largely unexplored. Recently, we demonstrated that the cystine...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502800/ https://www.ncbi.nlm.nih.gov/pubmed/31061420 http://dx.doi.org/10.1038/s41598-019-43285-5 |