Cargando…
Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development
A genetic contribution to refractive error has been confirmed by the discovery of more than 150 associated variants in genome-wide association studies (GWAS). Environmental factors such as education and time outdoors also demonstrate strong associations. Currently however, the extent of gene-environ...
Autores principales: | Pozarickij, Alfred, Williams, Cathy, Hysi, Pirro G., Guggenheim, Jeremy A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502837/ https://www.ncbi.nlm.nih.gov/pubmed/31069276 http://dx.doi.org/10.1038/s42003-019-0387-5 |
Ejemplares similares
-
Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia
por: Clark, Rosie, et al.
Publicado: (2022) -
Non-additive (dominance) effects of genetic variants associated with refractive error and myopia
por: Pozarickij, Alfred, et al.
Publicado: (2020) -
Novel Myopia Genes and Pathways Identified From Syndromic Forms of Myopia
por: Flitcroft, D. Ian, et al.
Publicado: (2018) -
Whole exome sequence analysis in 51 624 participants identifies novel genes and variants associated with refractive error and myopia
por: Guggenheim, Jeremy A, et al.
Publicado: (2022) -
Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia
por: Pozarickij, Alfred, et al.
Publicado: (2020)