Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart

Myocardial dysfunction is commonly associated with accumulation of cardiac lipid droplets (LDs). Perilipin 2 (Plin2) is a LD protein that is involved in LD formation, stability and trafficking events within the cell. Even though Plin2 is highly expressed in the heart, little is known about its role...

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Detalles Bibliográficos
Autores principales: Mardani, Ismena, Tomas Dalen, Knut, Drevinge, Christina, Miljanovic, Azra, Ståhlman, Marcus, Klevstig, Martina, Scharin Täng, Margareta, Fogelstrand, Per, Levin, Max, Ekstrand, Matias, Nair, Syam, Redfors, Björn, Omerovic, Elmir, Andersson, Linda, Kimmel, Alan R., Borén, Jan, Levin, Malin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502866/
https://www.ncbi.nlm.nih.gov/pubmed/31061399
http://dx.doi.org/10.1038/s41598-019-43335-y

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