IL-37 increases in patients after ischemic stroke and protects from inflammatory brain injury, motor impairment and lung infection in mice

Post-stroke inflammation may contribute to secondary brain injury and systemic immunosuppression. Interleukin(IL)-37 is an immunosuppressive cytokine belonging to the IL-1 superfamily with no mouse homologue yet identified, the effects of which have not been studied in stroke. Here we report: (1) th...

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Detalles Bibliográficos
Autores principales: Zhang, Shenpeng R., Nold, Marcel F., Tang, Sung-Chun, Bui, Christine B., Nold, Claudia A., Arumugam, Thiruma V., Drummond, Grant R., Sobey, Christopher G., Kim, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502884/
https://www.ncbi.nlm.nih.gov/pubmed/31061403
http://dx.doi.org/10.1038/s41598-019-43364-7

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