Cargando…

Foxc2 is essential for podocyte function

Foxc2 is one of the earliest podocyte markers during glomerular development. To circumvent embryonic lethal effects of global deletion of Foxc2, and to specifically investigate the role of Foxc2 in podocytes, we generated mice with a podocyte‐specific Foxc2 deletion. Mice carrying the homozygous del...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nilsson, Daniel, Heglind, Mikael, Arani, Zahra, Enerbäck, Sven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503019/ https://www.ncbi.nlm.nih.gov/pubmed/31062503 http://dx.doi.org/10.14814/phy2.14083

Ejemplares similares

The Adipocyte-Expressed Forkhead Transcription Factor Foxc2 Regulates Metabolism Through Altered Mitochondrial Function
por: Lidell, Martin E., et al.
Publicado: (2011)

Data supporting the regulation of FOXC2 in podocyte dysfunction
por: Datta, Neeta, et al.
Publicado: (2016)

Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazone
por: Håkansson, Joakim, et al.
Publicado: (2011)

The Forkhead Transcription Factor Foxi1 Is a Master Regulator of Vacuolar H(+)-ATPase Proton Pump Subunits in the Inner Ear, Kidney and Epididymis
por: Vidarsson, Hilmar, et al.
Publicado: (2009)

Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification
por: Almubarak, Asra, et al.
Publicado: (2021)

The transcription factor Dach1 is essential for podocyte function
por: Endlich, Nicole, et al.
Publicado: (2018)

All eyes on FOXC2
por: Yan, Wei, et al.
Publicado: (2023)

Regulation and Function of FOXC1 in Osteoblasts
por: Suthon, Sarocha, et al.
Publicado: (2023)

Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development
por: Seo, Seungwoon, et al.
Publicado: (2017)

Foxc1 and Foxc2 function in osteochondral progenitors for the progression through chondrocyte hypertrophy and mineralization of the primary ossification center
por: Almubarak, Asra, et al.
Publicado: (2023)

Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia–reperfusion injury
por: Tan, Can, et al.
Publicado: (2023)

Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation
por: Norden, Pieter R, et al.
Publicado: (2020)

Structural basis for DNA recognition by FOXC2
por: Chen, Xiaojuan, et al.
Publicado: (2019)

FOXC2 augments tumor propagation and metastasis in osteosarcoma
por: Gozo, Maricel C., et al.
Publicado: (2016)

FOXC2-AS1/FOXC2 axis mediates matrix stiffness-induced trans-differentiation of hepatic stellate cells into fibrosis-promoting myofibroblasts
por: Sun, Liankang, et al.
Publicado: (2023)

Functional polymorphisms in FOXC2 gene and Epithelial ovarian Cancer susceptibility in Chinese population
por: Zhou, Zhijiao, et al.
Publicado: (2020)

Effect of Insulin-Regulated FOXC2 Expression in Adipocyte Differentiation and Insulin Resistance
por: Zhang, Xuxiang, et al.
Publicado: (2020)

Crystal Structure of FOXC2 in Complex with DNA Target
por: Li, Shichang, et al.
Publicado: (2019)

FOXC2 Promotes Vasculogenic Mimicry in Ovarian Cancer
por: Recouvreux, Maria Sol, et al.
Publicado: (2022)

Downregulation of FoxC2 Increased Susceptibility to Experimental Colitis: Influence of Lymphatic Drainage Function?
por: Becker, Felix, et al.
Publicado: (2015)

FOXC1 and FOXC2 maintain mitral valve endothelial cell junctions, extracellular matrix, and lymphatic vessels to prevent myxomatous degeneration
por: Tan, Can, et al.
Publicado: (2023)

BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk
por: Bork, Tillmann, et al.
Publicado: (2022)

Differential roles of FOXC2 in the trabecular meshwork and Schlemm’s canal in glaucomatous pathology
por: Ujiie, Naoto, et al.
Publicado: (2023)

A nanoporous surface is essential for glomerular podocyte differentiation in three-dimensional culture
por: Zennaro, Cristina, et al.
Publicado: (2016)

Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus
por: Srivastava, Swayam Prakash, et al.
Publicado: (2021)

Cdk5 and Foxc2 – a new relationship in the lymphatic vasculature
por: Liebl, Johanna
Publicado: (2015)

FOXC2 Mutations in Familial and Sporadic Spinal Extradural Arachnoid Cyst
por: Ogura, Yoji, et al.
Publicado: (2013)

Meta-analysis of the prognostic significance of FOXC2 in various tumors
por: Xu, Bixia, et al.
Publicado: (2019)

The Role of FoxC2 Transcription Factor in Tumor Angiogenesis
por: Kume, Tsutomu
Publicado: (2012)

Role of FOXC2 and PITX2 rare variants associated with mild functional alterations as modifier factors in congenital glaucoma
por: Medina-Trillo, Cristina, et al.
Publicado: (2019)

Human venous valve disease caused by mutations in FOXC2 and GJC2
por: Lyons, Oliver, et al.
Publicado: (2017)

The Diverse Consequences of FOXC1 Deregulation in Cancer
por: Gilding, L. Niall, et al.
Publicado: (2019)

FOXC1, the new player in the cancer sandbox
por: Elian, Fahed A., et al.
Publicado: (2017)

Expression and Clinical Significance of the NCAPH, AGGF1, and FOXC2 Proteins in Serous Ovarian Cancer
por: Sun, Yingying, et al.
Publicado: (2021)

Up-Regulation of FOXC2 and FOXQ1 Is Associated with The Progression of Gastric-Type Adenocarcinoma
por: Soleimani, Farzad, et al.
Publicado: (2017)

LncRNA FOXC2-AS1 enhances FOXC2 mRNA stability to promote colorectal cancer progression via activation of Ca(2+)-FAK signal pathway
por: Pan, Ke, et al.
Publicado: (2020)

Foxc2 regulates osteogenesis and angiogenesis of bone marrow mesenchymal stem cells
por: You, Wulin, et al.
Publicado: (2013)

In silico analysis of single nucleotide polymorphisms (SNPs) in human FOXC2 gene
por: Nimir, Mohammed, et al.
Publicado: (2017)

Mesenchymal-Epithelial Transition in epithelial response to injury: the role of Foxc2
por: Hader, Carlos, et al.
Publicado: (2009)

A novel FOXC2 mutation in spinal extradural arachnoid cyst
por: Ogura, Yoji, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_m47a76kdguue39267dvav2chd1