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Sodium butyrate and panobinostat induce apoptosis of chronic myeloid leukemia cells via multiple pathways

PURPOSE: Histone deacetylase inhibitor (HDACI) is a novel therapeutic option for cancer. However, the effects of HDACIs on chronic myeloid leukemia (CML) and the underlying mechanisms are still unknown. The aim of this study was to investigate the effect and the mechanism‐of‐action of two HDACI memb...

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Detalles Bibliográficos
Autores principales: Jia, Xiaoyuan, Zheng, Yinsuo, Guo, Yanzi, Chen, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503025/
https://www.ncbi.nlm.nih.gov/pubmed/30891950
http://dx.doi.org/10.1002/mgg3.613

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