Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O(2) Consumption and ROS Release

Rett syndrome (RTT), an X chromosome-linked neurodevelopmental disorder affecting almost exclusively females, is associated with various mitochondrial alterations. Mitochondria are swollen, show altered respiratory rates, and their inner membrane is leaking protons. To advance the understanding of t...

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Detalles Bibliográficos
Autores principales: Can, Karolina, Menzfeld, Christiane, Rinne, Lena, Rehling, Peter, Kügler, Sebastian, Golubiani, Gocha, Dudek, Jan, Müller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503037/
https://www.ncbi.nlm.nih.gov/pubmed/31114506
http://dx.doi.org/10.3389/fphys.2019.00479

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