Detailed methylation map of LINE‐1 5′‐promoter region reveals hypomethylated CpG hotspots associated with tumor tissue specificity

BACKGROUND: Long interspersed nuclear elements (LINE‐1) sequences constitute a substantial portion of the human genome, and their methylation often correlating with global genomic methylation. Previous studies have highlighted the feasibility of using LINE‐1 methylation to discriminate tumors from h...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, Jamil, Muhammad A., Nuesgen, Nicole, Dauksa, Albertas, Gulbinas, Antanas, Schulz, Wolfgang A., Oldenburg, Johannes, El‐Maarri, Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503062/
https://www.ncbi.nlm.nih.gov/pubmed/30955237
http://dx.doi.org/10.1002/mgg3.601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503062/
https://www.ncbi.nlm.nih.gov/pubmed/30955237
http://dx.doi.org/10.1002/mgg3.601

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