Cargando…
Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing
CAR-NK cells may represent a valuable tool, complementary to CAR-T cells, in adoptive immunotherapy of leukemia and solid tumors. However, gene transfer to human NK cells is a challenging task, particularly with non-virus-based techniques. Here, we describe a new procedure allowing efficient electro...
Autores principales: | Ingegnere, Tiziano, Mariotti, Francesca Romana, Pelosi, Andrea, Quintarelli, Concetta, De Angelis, Biagio, Tumino, Nicola, Besi, Francesca, Cantoni, Claudia, Locatelli, Franco, Vacca, Paola, Moretta, Lorenzo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503170/ https://www.ncbi.nlm.nih.gov/pubmed/31114587 http://dx.doi.org/10.3389/fimmu.2019.00957 |
Ejemplares similares
-
PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression
por: Mariotti, Francesca R., et al.
Publicado: (2018) -
PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation
por: Tumino, Nicola, et al.
Publicado: (2019) -
Analysis of the mechanisms regulating soluble PD-1 production and function in human NK cells
por: Mariotti, Francesca Romana, et al.
Publicado: (2023) -
Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma
por: Tumino, Nicola, et al.
Publicado: (2021) -
Interaction Between MDSC and NK Cells in Solid and Hematological Malignancies: Impact on HSCT
por: Tumino, Nicola, et al.
Publicado: (2021)