Cargando…

Enhanced immunosuppressive effects of 3,5-bis[4(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one, an α, β-unsaturated carbonyl-based compound as PLGA-b-PEG nanoparticles

Background: 3,5-Bis[4-(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one (BBP), a novel synthetic curcumin analogue has been revealed to possess strong in vitro and in vivo immunosuppressive effects. Purpose: The aim of present study was to prepare and characterize BBP-encapsulated polylactic-co-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arshad, Laiba, Jantan, Ibrahim, Bukhari, Syed Nasir Abbas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503188/ https://www.ncbi.nlm.nih.gov/pubmed/31118577 http://dx.doi.org/10.2147/DDDT.S185191

Ejemplares similares

Immunosuppressive Effects of Natural α,β-Unsaturated Carbonyl-Based Compounds, and Their Analogs and Derivatives, on Immune Cells: A Review
por: Arshad, Laiba, et al.
Publicado: (2017)

4-Bromo-2-(diethoxymethyl)phenyl benzoate
por: Sharmila, P., et al.
Publicado: (2013)

Fluorinated and N-Acryloyl-Modified 3,5-Di[(E)-benzylidene]piperidin-4-one Curcuminoids for the Treatment of Pancreatic Carcinoma
por: Ghosh, Hindole, et al.
Publicado: (2023)

Antileishmanial and antitrypanosomal activity of symmetrical dibenzyl-substituted α,β-unsaturated carbonyl-based compounds
por: Alkhaldi, Abdulsalam AM, et al.
Publicado: (2019)

1-{3-[(4-Oxopiperidin-1-yl)carbonyl]benzoyl}piperidin-4-one
por: Rajesh, K., et al.
Publicado: (2010)

(3E,5E)-3,5-Bis(4-methylbenzylidene)-1-[3-(piperidin-1-yl)propanoyl]piperidin-4-one
por: Kia, Yalda, et al.
Publicado: (2012)

Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A
por: Tang, Li, et al.
Publicado: (2012)

(E)-2-[4-(Piperidin-1-yl)benzylidene]-2,3-dihydro-1H-inden-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

Crystal structure and Hirshfeld surface analysis of (E)-N′-[4-(piperidin-1-yl)benzylidene]arylsulfonohydrazides
por: Pai, Nikhila, et al.
Publicado: (2018)

Assessment of the Effect of PLGA Co-polymers and PEG on the Formation and Characteristics of PLGA-PEG-PLGA Co-block Polymer Using Statistical Approach
por: Sulaiman, Teuku Nanda Saifullah, et al.
Publicado: (2019)

1-Benzyl-3,5-bis(4-chlorobenzylidene)piperidin-4-one
por: Nesterov, Volodymyr V., et al.
Publicado: (2011)

3,5-Bis(4-chlorobenzylidene)-1-methylpiperidin-4-one
por: Nesterov, Volodymyr V., et al.
Publicado: (2011)

(3E,5E)-3,5-Bis(naphthalen-1-ylmethylidene)piperidin-4-one
por: Kia, Yalda, et al.
Publicado: (2012)

Immunosuppressive effects of the standardized extract of Phyllanthus amarus on cellular immune responses in Wistar-Kyoto rats
por: Ilangkovan, Menaga, et al.
Publicado: (2015)

DPD simulations on morphologies and structures of blank PLGA-b-PEG-b-PLGA polymeric micelles and docetaxel-loaded PLGA-b-PEG-b-PLGA polymeric micelles
por: Wang, Mengyao, et al.
Publicado: (2022)

PEG–PLGA nanoparticles for encapsulating ciprofloxacin
por: Watcharadulyarat, Natsorn, et al.
Publicado: (2023)

Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity
por: Chhikara, Aruna, et al.
Publicado: (2022)

4-[4-(Piperidin-1-yl)piperidin-1-yl]benzonitrile
por: Xu, Guo-bin, et al.
Publicado: (2010)

1,1,2,2-Tetrakis[2,4-dichloro-6-(diethoxymethyl)phenoxymethyl]ethene
por: Köysal, Yavuz, et al.
Publicado: (2012)

5′′-Benzylidene-5-chloro-1′,1′′-dimethyl-4′-phenyldispiro[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione
por: Farag, I. S. Ahmed, et al.
Publicado: (2013)

Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy
por: Heine, Sonja, et al.
Publicado: (2022)

(3E,5E)-3,5-Dibenzylidene-1-[3-(piperidin-1-yl)propanoyl]piperidin-4-one
por: Kia, Yalda, et al.
Publicado: (2011)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei, Pedram, et al.
Publicado: (2017)

Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles
por: Babos, György, et al.
Publicado: (2018)

Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
por: Fodor-Kardos, Andrea, et al.
Publicado: (2020)

Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model
por: Al-Thani, Hissa F., et al.
Publicado: (2022)

1-Acryloyl-2,6-bis(4-chlorophenyl)-3,5-dimethylpiperidin-4-one
por: Lakshminarayana, B. N., et al.
Publicado: (2009)

Crystal structures of 3,5-bis[(E)-3-hydroxybenzylidene]-1-methylpiperidin-4-one and 3,5-bis[(E)-2-chlorobenzylidene]-1-methylpiperidin-4-one
por: Eryanti, Yum, et al.
Publicado: (2015)

Drug-loaded PEG-PLGA nanoparticles for cancer treatment
por: Zhang, Dan, et al.
Publicado: (2022)

2-(4-Isopropylbenzylidene)propanoic acid
por: Muhammad, Niaz, et al.
Publicado: (2008)

1-{[5-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]}piperidin-4-one
por: Shahani, Tara, et al.
Publicado: (2010)

3-Cyclopropyl-1-(4-methylphenylsulfonyl)piperidine-3,5-diol
por: Wang, Yi, et al.
Publicado: (2011)

(3E,5E)-3,5-Dibenzylidene-1-phenethylpiperidin-4-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2011)

1-Benzyl-3,5-bis[(E)-3-thienylmethylidene]piperidin-4-one
por: Gayathri, P., et al.
Publicado: (2011)

1-Bromoacetyl-2,6-bis(4-methoxyphenyl)-3,5-dimethylpiperidin-4-one
por: Ramachandran, R., et al.
Publicado: (2008)

(3E,5E)-3,5-Bis(4-allyloxybenzylidene)-1-benzylpiperidin-4-one
por: Karthikeyan, N. S., et al.
Publicado: (2009)

Injectable In-Situ Forming Depot Based on PLGA and PLGA-PEG-PLGA for Sustained-Release of Risperidone: In Vitro Evaluation and Pharmacokinetics in Rabbits
por: Rezaeian Shiadeh, Seyedeh Nesa, et al.
Publicado: (2023)

1-[2,4,6-Trimethyl-3,5-bis(4-oxopiperidin-1-ylmethyl)benzyl]piperidin-4-one
por: Rajesh, K., et al.
Publicado: (2010)

An Insight Into the Modulatory Effects and Mechanisms of Action of Phyllanthus Species and Their Bioactive Metabolites on the Immune System
por: Jantan, Ibrahim, et al.
Publicado: (2019)

Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats
por: Rong, Xianfang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5petk37pptus41ftiro7dmbphu