Antitumor activity of larotrectinib in tumors harboring NTRK gene fusions: a short review on the current evidence

The development of deep-sequencing methods is now unveiling a new landscape of previously undetected gene fusion across different tumor types. Chromosomal translocation involving the NTRK gene family occur across a wide range of cancers in both children and adults. Preclinical studies have demonstra...

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Detalles Bibliográficos
Autores principales: Ricciuti, Biagio, Genova, Carlo, Crinò, Lucio, Libra, Massimo, Leonardi, Giulia Costanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503327/
https://www.ncbi.nlm.nih.gov/pubmed/31118670
http://dx.doi.org/10.2147/OTT.S177051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503327/
https://www.ncbi.nlm.nih.gov/pubmed/31118670
http://dx.doi.org/10.2147/OTT.S177051

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