Cargando…
Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds
[Image: see text] Transcriptional repressor EthR from Mycobacterium tuberculosis is a valuable target for antibiotic booster drugs. We previously reported a virtual screening campaign to identify EthR inhibitors for development. Two ligand binding orientations were often proposed, though only the to...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503467/ https://www.ncbi.nlm.nih.gov/pubmed/30965004 http://dx.doi.org/10.1021/acs.jpclett.9b00741 |