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Correlation of Milestone Restricted Mean Survival Time Ratio With Overall Survival Hazard Ratio in Randomized Clinical Trials of Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis

IMPORTANCE: Immune checkpoint inhibitors (ICIs) have unique patterns of response and survival that differ from conventional chemotherapies. Novel intermediate end points are urgently required to detect the early signals of ICI activity. OBJECTIVE: To evaluate milestone rate (Kaplan-Meier estimates o...

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Detalles Bibliográficos
Autores principales:	Wang, Zi-Xian, Wu, Hao-Xiang, Xie, Li, Wang, Ying-Nan, Yang, Lu-Ping, He, Ming-Ming, Luo, Hui-Yan, Ding, Pei-Rong, Xie, Dan, Chen, Gong, Li, Yu-Hong, Wang, Feng, Xu, Rui-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2019
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503508/ https://www.ncbi.nlm.nih.gov/pubmed/31050784 http://dx.doi.org/10.1001/jamanetworkopen.2019.3433

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