Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation

[Image: see text] Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal–ligand cooperation of the mangan...

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Autores principales: Zou, You-Quan, Chakraborty, Subrata, Nerush, Alexander, Oren, Dror, Diskin-Posner, Yael, Ben-David, Yehoshoa, Milstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503579/
https://www.ncbi.nlm.nih.gov/pubmed/31080688
http://dx.doi.org/10.1021/acscatal.8b02902
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author Zou, You-Quan
Chakraborty, Subrata
Nerush, Alexander
Oren, Dror
Diskin-Posner, Yael
Ben-David, Yehoshoa
Milstein, David
author_facet Zou, You-Quan
Chakraborty, Subrata
Nerush, Alexander
Oren, Dror
Diskin-Posner, Yael
Ben-David, Yehoshoa
Milstein, David
author_sort Zou, You-Quan
collection PubMed
description [Image: see text] Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal–ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions.
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spelling pubmed-65035792019-05-08 Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation Zou, You-Quan Chakraborty, Subrata Nerush, Alexander Oren, Dror Diskin-Posner, Yael Ben-David, Yehoshoa Milstein, David ACS Catal [Image: see text] Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal–ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions. American Chemical Society 2018-07-30 2018-09-07 /pmc/articles/PMC6503579/ /pubmed/31080688 http://dx.doi.org/10.1021/acscatal.8b02902 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Zou, You-Quan
Chakraborty, Subrata
Nerush, Alexander
Oren, Dror
Diskin-Posner, Yael
Ben-David, Yehoshoa
Milstein, David
Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation
title Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation
title_full Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation
title_fullStr Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation
title_full_unstemmed Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation
title_short Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal–Ligand Cooperation
title_sort highly selective, efficient deoxygenative hydrogenation of amides catalyzed by a manganese pincer complex via metal–ligand cooperation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503579/
https://www.ncbi.nlm.nih.gov/pubmed/31080688
http://dx.doi.org/10.1021/acscatal.8b02902
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