Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein

[Image: see text] Artificial metalloenzymes combine a synthetic metallocofactor with a protein scaffold and can catalyze abiotic reactions in vivo. Herein, we report on our efforts to valorize human carbonic anhydrase II as a scaffold for whole-cell transfer hydrogenation. Two platforms were tested:...

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Detalles Bibliográficos
Autores principales: Rebelein, Johannes G., Cotelle, Yoann, Garabedian, Brett, Ward, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503580/
https://www.ncbi.nlm.nih.gov/pubmed/31080690
http://dx.doi.org/10.1021/acscatal.9b01006

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