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NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses

NOD2 and TLR2 recognize components of bacterial cell wall peptidoglycan and direct defense against enteric pathogens. CD8(+) T cells are important for immunity to such pathogens but how NOD2 and TLR2 induce antigen specific CD8(+) T cell responses is unknown. Here, we define how these pattern recogn...

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Detalles Bibliográficos
Autores principales:	Corridoni, Daniele, Shiraishi, Seiji, Chapman, Thomas, Steevels, Tessa, Muraro, Daniele, Thézénas, Marie-Laëtitia, Prota, Gennaro, Chen, Ji-Li, Gileadi, Uzi, Ternette, Nicola, Cerundolo, Vincenzo, Simmons, Alison
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503738/ https://www.ncbi.nlm.nih.gov/pubmed/31114588 http://dx.doi.org/10.3389/fimmu.2019.00958

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