Estrogen Modulates Cartilage and Subchondral Bone Remodeling in an Ovariectomized Rat Model of Postmenopausal Osteoarthritis

BACKGROUND: Estrogen levels regulate changes in osteoarthritis (OA) by inhibiting degradation of the extracellular matrix. Recent in vitro studies have also shown the role of microRNA-140-5p (miR-140-5p). This study aimed to investigate the role of estrogen deficiency, selective modulation of expres...

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Detalles Bibliográficos
Autores principales: Xu, Xiao, Li, Xingfu, Liang, Yujie, Ou, Yangkan, Huang, Junfeng, Xiong, Jianyi, Duan, Li, Wang, Daping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503753/
https://www.ncbi.nlm.nih.gov/pubmed/31031401
http://dx.doi.org/10.12659/MSM.916254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503753/
https://www.ncbi.nlm.nih.gov/pubmed/31031401
http://dx.doi.org/10.12659/MSM.916254

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