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Estrogen Modulates Cartilage and Subchondral Bone Remodeling in an Ovariectomized Rat Model of Postmenopausal Osteoarthritis
BACKGROUND: Estrogen levels regulate changes in osteoarthritis (OA) by inhibiting degradation of the extracellular matrix. Recent in vitro studies have also shown the role of microRNA-140-5p (miR-140-5p). This study aimed to investigate the role of estrogen deficiency, selective modulation of expres...
Autores principales: | Xu, Xiao, Li, Xingfu, Liang, Yujie, Ou, Yangkan, Huang, Junfeng, Xiong, Jianyi, Duan, Li, Wang, Daping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503753/ https://www.ncbi.nlm.nih.gov/pubmed/31031401 http://dx.doi.org/10.12659/MSM.916254 |
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