Cargando…

Loss of CDKN2A and CDKN2B expression is associated with disease recurrence in oral cancer

BACKGROUND: Loco-regional recurrence is one of the major reasons for poor prognosis of oral squamous cell carcinoma (OSCC). However, till date, no feasible molecular marker is available to predict the risk of recurrence in OSCC patients. AIM: To evaluate the cell cycle regulatory genes expression an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deepak Roshan, V G, Sinto, M S, Vargees, Bipin T, Kannan, S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503771/ https://www.ncbi.nlm.nih.gov/pubmed/31110422 http://dx.doi.org/10.4103/jomfp.JOMFP_184_18

Ejemplares similares

Loss of Both CDKN2A and CDKN2B Allows for Centrosome Overduplication in Melanoma
por: Patel, Shyamal, et al.
Publicado: (2020)

Association Study of Genetic Variants in CDKN2A/CDKN2B Genes/Loci with Late-Onset Alzheimer's Disease
por: Tedde, Andrea, et al.
Publicado: (2011)

Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B
por: Soto, José Luis, et al.
Publicado: (2005)

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas
por: Sievers, Philipp, et al.
Publicado: (2020)

Molecular Genetics and Functional Analysis Implicate CDKN2BAS1-CDKN2B Involvement in POAG Pathogenesis
por: Rathi, Sonika, et al.
Publicado: (2020)

Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours.
por: Schmidt, E. E., et al.
Publicado: (1997)

Association of CDKN2A/CDKN2B Gene Polymorphisms with Increased Susceptibility to Intracranial Aneurysm in a Chinese Han Population
por: Cui, Xiaopeng, et al.
Publicado: (2021)

Germline hemizygous deletion of CDKN2A–CDKN2B locus in a patient presenting with Li–Fraumeni syndrome
por: Chan, Sock Hoai, et al.
Publicado: (2016)

Promoter hypermethylation inactivates CDKN2A, CDKN2B and RASSF1A genes in sporadic parathyroid adenomas
por: Arya, Ashutosh Kumar, et al.
Publicado: (2017)

Novel germline variants of CDKN1B and CDKN2C identified during screening for familial primary hyperparathyroidism
por: Mazarico-Altisent, I., et al.
Publicado: (2022)

Roles of CDKN1B in cancer?
por: Belletti, Barbara, et al.
Publicado: (2015)

CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A
por: Tu, Q, et al.
Publicado: (2018)

The Yin and Yang-Like Clinical Implications of the CDKN2A/ARF/CDKN2B Gene Cluster in Acute Lymphoblastic Leukemia
por: González-Gil, Celia, et al.
Publicado: (2021)

Association of Myocardial Infarction with CDKN2B Antisense RNA 1 (CDKN2B-AS1) rs1333049 Polymorphism in Slovenian Subjects with Type 2 Diabetes Mellitus
por: Tibaut, Miha, et al.
Publicado: (2022)

Blood CDKN2A Gene Expression in Aging and Neurodegenerative Diseases
por: Mori, Hiroaki, et al.
Publicado: (2021)

CDKN2B Methylation Correlates with Survival in AML Patients
por: Kamali Dolatabadi, Esmat, et al.
Publicado: (2017)

Tbx2 Controls Lung Growth by Direct Repression of the Cell Cycle Inhibitor Genes Cdkn1a and Cdkn1b
por: Lüdtke, Timo H-W., et al.
Publicado: (2013)

Dual Suppression of the Cyclin-Dependent Kinase Inhibitors CDKN2C and CDKN1A in Human Melanoma
por: Jalili, Ahmad, et al.
Publicado: (2012)

Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter
por: Ou, Minghui, et al.
Publicado: (2020)

CDKN3 expression is negatively associated with pathological tumor stage and CDKN3 inhibition promotes cell survival in hepatocellular carcinoma
por: Dai, Wei, et al.
Publicado: (2016)

Effects of CDKN2B‐AS1 polymorphisms on the susceptibility to coronary heart disease
por: Huang, Kang, et al.
Publicado: (2019)

Ezh2 Regulates Activation-Induced CD8(+) T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression
por: Chen, Guobing, et al.
Publicado: (2018)

Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma
por: Cagney, Daniel N, et al.
Publicado: (2019)

Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss
por: Frisone, Daniele, et al.
Publicado: (2019)

Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis
por: Thakur, Nanamika, et al.
Publicado: (2021)

Recurrent copy number alterations involving EGFR , CDKN2A , and CCND1 in oral premalignant lesions
por: Jäwert, Fredrik, et al.
Publicado: (2022)

The hypermethylation of the CDKN2A and CHFR promoter region is a key regulatory mechanism of CDKN2A and CHFR expression in esophageal squamous cell carcinoma
por: Mei, Xinyu, et al.
Publicado: (2019)

Mysterious link between iron overload and CDKN2A/2B
por: Toyokuni, Shinya
Publicado: (2011)

CDKN2D-WDFY2 Is a Cancer-Specific Fusion Gene Recurrent in High-Grade Serous Ovarian Carcinoma
por: Kannan, Kalpana, et al.
Publicado: (2014)

Exome Sequencing with Validations and Expression of p16/CDKN2A Shows no Association with HPV in Oral Cancers
por: Shyamsundar, Vidyarani, et al.
Publicado: (2022)

Detection and significance of human papillomavirus, CDKN2A (p16) and CDKN1A (p21) expression in squamous cell carcinoma of the larynx
por: Chernock, Rebecca D., et al.
Publicado: (2012)

Surveillance, CDKN2A and survival of familial melanoma
por: van Doorn, Remco
Publicado: (2023)

Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia
por: Genescà, E., et al.
Publicado: (2018)

Interactive effects of CDKN2B‐AS1 gene polymorphism and habitual risk factors on oral cancer
por: Yeh, Jung‐Chun, et al.
Publicado: (2023)

CDKN2B methylation is associated with carotid artery calcification in ischemic stroke patients
por: Zhou, Shuyu, et al.
Publicado: (2016)

Epigenetic silencing of CDKN1A and CDKN2B by SNHG1 promotes the cell cycle, migration and epithelial-mesenchymal transition progression of hepatocellular carcinoma
por: Li, Bei, et al.
Publicado: (2020)

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia
por: Jang, Woori, et al.
Publicado: (2019)

CDKN2B Methylation and Aortic Arch Calcification in Patients with Ischemic Stroke
por: Zhou, Shuyu, et al.
Publicado: (2017)

CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma
por: Hu, Zhenxian, et al.
Publicado: (2017)

CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review
por: Yuile, Alexander, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dc9pl4e9so7kl4bje3rp1n1ra1