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SIRT6 participates in the quality control of aged oocytes via modulating telomere function

It has been well recognized that oocyte quality declines in aging animals. However, to date, the underlying mechanism remains to be explored. In the present study, we report that oocytes and embryos from aged mice (42-45 weeks old) display the reduced expression of SIRT6 protein, accompanying with t...

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Detalles Bibliográficos
Autores principales: Ge, Juan, Li, Congyang, Li, Chunling, Huang, Zhenyue, Zeng, Juan, Han, Longsen, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503879/
https://www.ncbi.nlm.nih.gov/pubmed/30926765
http://dx.doi.org/10.18632/aging.101885