The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity

The elaboration of polarity is central to organismal development and to the maintenance of functional epithelia. Among the controls determining polarity are the PAR proteins, PAR6, aPKCι and PAR3, regulating both known and unknown effectors. Here, we identify FARP2 as a ‘RIPR’ motif-dependent partne...

Descripción completa

Detalles Bibliográficos
Autores principales: Elbediwy, Ahmed, Zhang, Yixiao, Cobbaut, Mathias, Riou, Philippe, Tan, Ray S., Roberts, Selene K., Tynan, Chris, George, Roger, Kjaer, Svend, Martin-Fernandez, Marisa L., Thompson, Barry J., McDonald, Neil Q., Parker, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503954/
https://www.ncbi.nlm.nih.gov/pubmed/30872454
http://dx.doi.org/10.1242/jcs.223743

Ejemplares similares

Ejemplares similares