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Distinct gene-selective roles for a network of core promoter factors in Drosophila neural stem cell identity

The transcriptional mechanisms that allow neural stem cells (NSC) to balance self-renewal with differentiation are not well understood. Employing an in vivo RNAi screen we identify here NSC-TAFs, a subset of nine TATA-binding protein associated factors (TAFs), as NSC identity genes in Drosophila. We...

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Detalles Bibliográficos
Autores principales:	Neves, Alexandre, Eisenman, Robert N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504003/ https://www.ncbi.nlm.nih.gov/pubmed/30948355 http://dx.doi.org/10.1242/bio.042168

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