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DNA methylome of human neonatal umbilical cord: Enrichment of differentially methylated regions compared to umbilical cord blood DNA at transcription factor genes involved in body patterning and effects of maternal folate deficiency or children’s sex
The DOHaD (developmental origins of health and disease) hypothesis claims that fetal malnutrition or exposure to environmental pollutants may affect their lifelong health. Epigenetic changes may play significant roles in DOHaD; however, access to human fetuses for research has ethical and technical...
Autores principales: | Sakurai, Kenichi, Shioda, Keiko, Eguchi, Akifumi, Watanabe, Masahiro, Miyaso, Hidenori, Mori, Chisato, Shioda, Toshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504184/ https://www.ncbi.nlm.nih.gov/pubmed/31063509 http://dx.doi.org/10.1371/journal.pone.0214307 |
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