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Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

PURPOSE: Reduced nuclear expression of BRCA1 associated protein 1 (BAP-1) is associated with a high risk for metastasis in uveal melanoma. Manual assessment of the expression level may face issues with interobserver reproducibility. This could be improved with digital image analysis (DIA). METHODS:...

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Detalles Bibliográficos
Autores principales: Stålhammar, Gustav, See, Thonnie Rose O., Phillips, Stephen, Seregard, Stefan, Grossniklaus, Hans E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504204/
https://www.ncbi.nlm.nih.gov/pubmed/31110912
http://dx.doi.org/10.1167/tvst.8.3.11