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PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma

Glioblastoma (GBM) is the most malignant brain tumor with profound genomic alterations. Tumor suppressor genes regulate multiple signaling networks that restrict cellular proliferation and present barriers to malignant transformation. While bona fide tumor suppressors such as PTEN and TP53 often und...

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Detalles Bibliográficos
Autores principales:	Shin, Yong Jae, Sa, Jason K., Lee, Yeri, Kim, Donggeon, Chang, Nakho, Cho, Hee Jin, Son, Miseol, Oh, Michael Y.T., Shin, Kayoung, Lee, Jin-Ku, Park, Jiwon, Jo, Yoon Kyung, Kim, Misuk, Paddison, Patrick J., Tergaonkar, Vinay, Lee, Jeongwu, Nam, Do-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504209/ https://www.ncbi.nlm.nih.gov/pubmed/30898893 http://dx.doi.org/10.1084/jem.20172170

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