Cargando…

Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques

Subclinical hypothyroidism is associated with cardiovascular diseases, yet the underlying mechanism remains largely unknown. Herein, in a common population (n = 1,103), TSH level was found to be independently correlated with both carotid plaque prevalence and intima-media thickness. Consistently, TS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chongbo, Lu, Ming, Chen, Wenbin, He, Zhao, Hou, Xu, Feng, Mei, Zhang, Hongjia, Bo, Tao, Zhou, Xiaoming, Yu, Yong, Zhang, Haiqing, Zhao, Meng, Wang, Laicheng, Yu, Chunxiao, Gao, Ling, Jiang, Wenjian, Zhang, Qunye, Zhao, Jiajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504213/ https://www.ncbi.nlm.nih.gov/pubmed/30940720 http://dx.doi.org/10.1084/jem.20181473

Ejemplares similares

Correction: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
por: Yang, Chongbo, et al.
Publicado: (2022)

Immune Checkpoint Inhibitor Therapy Aggravates T Cell–Driven Plaque Inflammation in Atherosclerosis
por: Poels, Kikkie, et al.
Publicado: (2020)

Thyrotropin and Obesity: Increased Adipose Triglyceride Content Through Glycerol-3-Phosphate Acyltransferase 3
por: Ma, Shizhan, et al.
Publicado: (2015)

Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway
por: Niu, Shaona, et al.
Publicado: (2018)

A reduction of Syndecan-4 in macrophages promotes atherosclerosis by aggravating the proinflammatory capacity of macrophages
por: Hu, Jiaxin, et al.
Publicado: (2022)

Corrigendum to “Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway”
por: Niu, Shaona, et al.
Publicado: (2018)

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis
por: Beldman, Thijs J., et al.
Publicado: (2017)

The G2A Receptor Deficiency Aggravates Atherosclerosis in Rats by Regulating Macrophages and Lipid Metabolism
por: Cui, Xueqin, et al.
Publicado: (2021)

A Single-Cell Atlas of the Atherosclerotic Plaque in the Femoral Artery and the Heterogeneity in Macrophage Subtypes between Carotid and Femoral Atherosclerosis
por: Wang, Ping, et al.
Publicado: (2022)

YKL-40 Aggravates Early-Stage Atherosclerosis by Inhibiting Macrophage Apoptosis in an Aven-dependent Way
por: Huan, Wei, et al.
Publicado: (2021)

Oral pathogen aggravates atherosclerosis by inducing smooth muscle cell apoptosis and repressing macrophage efferocytosis
por: Xie, Hanyu, et al.
Publicado: (2023)

Regression of Atherosclerosis Is Characterized by Broad Changes in the Plaque Macrophage Transcriptome
por: Feig, Jonathan E., et al.
Publicado: (2012)

The Role of Monocytes and Macrophages in Human Atherosclerosis, Plaque Neoangiogenesis, and Atherothrombosis
por: Moroni, Francesco, et al.
Publicado: (2019)

Plaque‐Targeted Rapamycin Spherical Nucleic Acids for Synergistic Atherosclerosis Treatment
por: Guo, Yuanyuan, et al.
Publicado: (2022)

Comparison of Erythrocyte Membrane Lipid Profiles between NAFLD Patients with or without Hyperlipidemia
por: Chen, Wenbin, et al.
Publicado: (2020)

Follicle-Stimulating Hormone Increases the Risk of Postmenopausal Osteoporosis by Stimulating Osteoclast Differentiation
por: Wang, Jie, et al.
Publicado: (2015)

Batf3-dependent CD8α(+) Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages
por: Li, Yalin, et al.
Publicado: (2017)

Imaging of Oxidation-Specific Epitopes in Atherosclerosis and Macrophage-Rich Vulnerable Plaques
por: Briley-Saebo, Karen C., et al.
Publicado: (2010)

Characteristics of plaque lipid-associated macrophages and their possible roles in the pathogenesis of atherosclerosis
por: Kim, Kyeongdae, et al.
Publicado: (2022)

Sphingosine-1-Phosphate (S1P) Lyase Inhibition Aggravates Atherosclerosis and Induces Plaque Rupture in ApoE(−/−) Mice
por: Keul, Petra, et al.
Publicado: (2022)

Neutrophil extracellular traps-mediated Beclin-1 suppression aggravates atherosclerosis by inhibiting macrophage autophagy
por: Sano, Masataka, et al.
Publicado: (2022)

DNA hydroxymethylation combined with carotid plaques as a novel biomarker for coronary atherosclerosis
por: Jiang, Dan, et al.
Publicado: (2019)

Presence of thyrotropin receptor in hepatocytes: not a case of illegitimate transcription
por: Zhang, Wei, et al.
Publicado: (2009)

Advanced targeted nanomedicines for vulnerable atherosclerosis plaque imaging and their potential clinical implications
por: Li, Xue, et al.
Publicado: (2022)

Theranostic nanoplatform to target macrophages enables the inhibition of atherosclerosis progression and fluorescence imaging of plaque in ApoE(−/−) mice
por: Wang, Qi, et al.
Publicado: (2021)

Relation of ABO Blood Groups to the Plaque Characteristic of Coronary Atherosclerosis
por: Huang, Xingtao, et al.
Publicado: (2017)

Gene silencing of TACE enhances plaque stability and improves vascular remodeling in a rabbit model of atherosclerosis
por: Zhao, Xueqiang, et al.
Publicado: (2015)

Association of Preconception Thyrotropin Levels With Fecundability and Risk of Spontaneous Abortion in China
por: Yang, Ying, et al.
Publicado: (2022)

Perivascular Adipose Tissue-Derived Adiponectin Inhibits Collar-Induced Carotid Atherosclerosis by Promoting Macrophage Autophagy
por: Li, Changlong, et al.
Publicado: (2015)

Targeting ApoC3 Paradoxically Aggravates Atherosclerosis in Hamsters With Severe Refractory Hypercholesterolemia
por: Xu, Yitong, et al.
Publicado: (2022)

Deep sequencing of the T cell receptor β repertoire reveals signature patterns and clonal drift in atherosclerotic plaques and patients
por: Lin, Zongwei, et al.
Publicado: (2017)

Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis
por: Li, Shanshan, et al.
Publicado: (2019)

Molecular basis for the activation of thyrotropin-releasing hormone receptor
por: Ji, Su-Yu, et al.
Publicado: (2022)

The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis
por: Geng, Shuo, et al.
Publicado: (2016)

The Relation between Atherosclerosis Plaque Composition and Plaque Rupture
por: Babaniamansour, Parto, et al.
Publicado: (2020)

Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway
por: Meng, Da, et al.
Publicado: (2023)

Macrophage-specific autophagy-related gene HSPB8 is involved in the macrophage polarization in atherosclerosis
por: Wang, Juping, et al.
Publicado: (2023)

Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability
por: Shen, Xinyi, et al.
Publicado: (2021)

Ferroptosis: A potential target of macrophages in plaque vulnerability
por: Li, Yu, et al.
Publicado: (2023)

Case Report and Literature Review: Ectopic Thyrotropin-Secreting Pituitary Adenoma in the Suprasellar Region
por: Li, Xiaoxu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ksgtrtam6cbii8gjcfspifi8su