Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

Liquid biopsies allow monitoring of cancer progression and detection of relapse, but reliable biomarkers in melanoma are lacking. Because secreted factors preferentially drain to lymphatic vessels before dilution in the blood, we hypothesized that lymph should be vastly enriched in cancer biomarkers...

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Detalles Bibliográficos
Autores principales: Broggi, Maria A.S., Maillat, Lea, Clement, Cristina C., Bordry, Natacha, Corthésy, Patricia, Auger, Aymeric, Matter, Maurice, Hamelin, Romain, Potin, Lambert, Demurtas, Davide, Romano, Emanuela, Harari, Alexandre, Speiser, Daniel E., Santambrogio, Laura, Swartz, Melody A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504224/
https://www.ncbi.nlm.nih.gov/pubmed/30975896
http://dx.doi.org/10.1084/jem.20181618

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