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Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons

Toxoplasma gondii is an important human and animal pathogen that causes life-threatening toxoplasmosis. The host immune system produces interferon-γ (IFN-γ) to inhibit T. gondii proliferation. IFN-γ-inducible indole-2,3-dioxygenase 1 (IDO1), which mediates tryptophan degradation, has a major role in...

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Detalles Bibliográficos
Autores principales:	Bando, Hironori, Lee, Youngae, Sakaguchi, Naoya, Pradipta, Ariel, Sakamoto, Ryoma, Tanaka, Shun, Ma, Ji Su, Sasai, Miwa, Yamamoto, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504700/ https://www.ncbi.nlm.nih.gov/pubmed/31119110 http://dx.doi.org/10.3389/fcimb.2019.00140

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