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Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report

PURPOSE: Corneal collagen cross-linking (CXL) has become the standard initial intervention in eyes with progressive keratoconus (KC) that have not undergone keratoplasty. The prolonged exposure of the de-epithelialized cornea predisposes it to adverse complications, such as microbial keratitis and m...

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Autores principales: Faramarzi, Amir, Hassanpour, Kiana, Roshandel, Danial, Fatourechi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504722/
https://www.ncbi.nlm.nih.gov/pubmed/31114658
http://dx.doi.org/10.4103/jovr.jovr_100_18
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author Faramarzi, Amir
Hassanpour, Kiana
Roshandel, Danial
Fatourechi, Ali
author_facet Faramarzi, Amir
Hassanpour, Kiana
Roshandel, Danial
Fatourechi, Ali
author_sort Faramarzi, Amir
collection PubMed
description PURPOSE: Corneal collagen cross-linking (CXL) has become the standard initial intervention in eyes with progressive keratoconus (KC) that have not undergone keratoplasty. The prolonged exposure of the de-epithelialized cornea predisposes it to adverse complications, such as microbial keratitis and melting. Herein, we report a case of bilateral recurrent peripheral stromal keratitis following CXL. CASE REPORT: We present a 29-year-old woman who complained of ocular redness and discomfort in both eyes for 4 months, and had undergone bilateral CXL 10 months before. The best spectacle corrected visual acuity (BSCVA) was 60/200 in the right and 80/200 in the left eye. Both eyes showed moderate conjunctival hyperemia, dilation, and engorgement of the perilimbal episcleral vessels. There was a peripheral corneal stromal infiltration with thinning, and an overlying epithelial defect in the right eye with a lucid interval from the limbus. She was treated with lubricating eye drops and ointments and topical corticosteroids every 4 hours for 2 weeks then slowly tapered off. Afterwards, she experienced multiple recurrences in both eyes, which were successfully managed with topical corticosteroids and lubricants. After 2 years, her BSCVA was 20/30 with −3.00-5.50 * 90 in the right eye and 20/40 with −4.00-4.50 * 90 in the left. CONCLUSION: Although CXL is a safe method, studies with longer follow-ups are needed to investigate the risk of rare complications.
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spelling pubmed-65047222019-05-21 Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report Faramarzi, Amir Hassanpour, Kiana Roshandel, Danial Fatourechi, Ali J Ophthalmic Vis Res Case Report PURPOSE: Corneal collagen cross-linking (CXL) has become the standard initial intervention in eyes with progressive keratoconus (KC) that have not undergone keratoplasty. The prolonged exposure of the de-epithelialized cornea predisposes it to adverse complications, such as microbial keratitis and melting. Herein, we report a case of bilateral recurrent peripheral stromal keratitis following CXL. CASE REPORT: We present a 29-year-old woman who complained of ocular redness and discomfort in both eyes for 4 months, and had undergone bilateral CXL 10 months before. The best spectacle corrected visual acuity (BSCVA) was 60/200 in the right and 80/200 in the left eye. Both eyes showed moderate conjunctival hyperemia, dilation, and engorgement of the perilimbal episcleral vessels. There was a peripheral corneal stromal infiltration with thinning, and an overlying epithelial defect in the right eye with a lucid interval from the limbus. She was treated with lubricating eye drops and ointments and topical corticosteroids every 4 hours for 2 weeks then slowly tapered off. Afterwards, she experienced multiple recurrences in both eyes, which were successfully managed with topical corticosteroids and lubricants. After 2 years, her BSCVA was 20/30 with −3.00-5.50 * 90 in the right eye and 20/40 with −4.00-4.50 * 90 in the left. CONCLUSION: Although CXL is a safe method, studies with longer follow-ups are needed to investigate the risk of rare complications. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6504722/ /pubmed/31114658 http://dx.doi.org/10.4103/jovr.jovr_100_18 Text en Copyright: © 2019 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Faramarzi, Amir
Hassanpour, Kiana
Roshandel, Danial
Fatourechi, Ali
Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report
title Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report
title_full Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report
title_fullStr Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report
title_full_unstemmed Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report
title_short Recurrent Peripheral Stromal Keratitis Following Corneal Collagen Cross-linking: A Case Report
title_sort recurrent peripheral stromal keratitis following corneal collagen cross-linking: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504722/
https://www.ncbi.nlm.nih.gov/pubmed/31114658
http://dx.doi.org/10.4103/jovr.jovr_100_18
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