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Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy

PURPOSE: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. METHODS: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acut...

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Autores principales: Hanumunthadu, Daren, van Dijk, Elon H. C., Dumpala, Sunila, Rajesh, Bindu, Jabeen, Ayesha, Jabeen, Asiya, Ansari, Momin, Mehta, Pooja, Shah, Shilpi, Sarvaiya, Chintan, Meyerle, Catherine, Wu, Lihteh, Banker, Alay, Boon, Camiel J., Chhablani, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504723/
https://www.ncbi.nlm.nih.gov/pubmed/31114653
http://dx.doi.org/10.4103/jovr.jovr_152_17
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author Hanumunthadu, Daren
van Dijk, Elon H. C.
Dumpala, Sunila
Rajesh, Bindu
Jabeen, Ayesha
Jabeen, Asiya
Ansari, Momin
Mehta, Pooja
Shah, Shilpi
Sarvaiya, Chintan
Meyerle, Catherine
Wu, Lihteh
Banker, Alay
Boon, Camiel J.
Chhablani, Jay
author_facet Hanumunthadu, Daren
van Dijk, Elon H. C.
Dumpala, Sunila
Rajesh, Bindu
Jabeen, Ayesha
Jabeen, Asiya
Ansari, Momin
Mehta, Pooja
Shah, Shilpi
Sarvaiya, Chintan
Meyerle, Catherine
Wu, Lihteh
Banker, Alay
Boon, Camiel J.
Chhablani, Jay
author_sort Hanumunthadu, Daren
collection PubMed
description PURPOSE: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. METHODS: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). RESULTS: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. CONCLUSION: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes.
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spelling pubmed-65047232019-05-21 Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy Hanumunthadu, Daren van Dijk, Elon H. C. Dumpala, Sunila Rajesh, Bindu Jabeen, Ayesha Jabeen, Asiya Ansari, Momin Mehta, Pooja Shah, Shilpi Sarvaiya, Chintan Meyerle, Catherine Wu, Lihteh Banker, Alay Boon, Camiel J. Chhablani, Jay J Ophthalmic Vis Res Original Article PURPOSE: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. METHODS: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). RESULTS: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. CONCLUSION: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6504723/ /pubmed/31114653 http://dx.doi.org/10.4103/jovr.jovr_152_17 Text en Copyright: © 2019 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Hanumunthadu, Daren
van Dijk, Elon H. C.
Dumpala, Sunila
Rajesh, Bindu
Jabeen, Ayesha
Jabeen, Asiya
Ansari, Momin
Mehta, Pooja
Shah, Shilpi
Sarvaiya, Chintan
Meyerle, Catherine
Wu, Lihteh
Banker, Alay
Boon, Camiel J.
Chhablani, Jay
Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
title Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
title_full Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
title_fullStr Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
title_full_unstemmed Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
title_short Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
title_sort evaluation of choroidal layer thickness in central serous chorioretinopathy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504723/
https://www.ncbi.nlm.nih.gov/pubmed/31114653
http://dx.doi.org/10.4103/jovr.jovr_152_17
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