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Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy
PURPOSE: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. METHODS: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acut...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504723/ https://www.ncbi.nlm.nih.gov/pubmed/31114653 http://dx.doi.org/10.4103/jovr.jovr_152_17 |
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author | Hanumunthadu, Daren van Dijk, Elon H. C. Dumpala, Sunila Rajesh, Bindu Jabeen, Ayesha Jabeen, Asiya Ansari, Momin Mehta, Pooja Shah, Shilpi Sarvaiya, Chintan Meyerle, Catherine Wu, Lihteh Banker, Alay Boon, Camiel J. Chhablani, Jay |
author_facet | Hanumunthadu, Daren van Dijk, Elon H. C. Dumpala, Sunila Rajesh, Bindu Jabeen, Ayesha Jabeen, Asiya Ansari, Momin Mehta, Pooja Shah, Shilpi Sarvaiya, Chintan Meyerle, Catherine Wu, Lihteh Banker, Alay Boon, Camiel J. Chhablani, Jay |
author_sort | Hanumunthadu, Daren |
collection | PubMed |
description | PURPOSE: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. METHODS: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). RESULTS: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. CONCLUSION: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes. |
format | Online Article Text |
id | pubmed-6504723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-65047232019-05-21 Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy Hanumunthadu, Daren van Dijk, Elon H. C. Dumpala, Sunila Rajesh, Bindu Jabeen, Ayesha Jabeen, Asiya Ansari, Momin Mehta, Pooja Shah, Shilpi Sarvaiya, Chintan Meyerle, Catherine Wu, Lihteh Banker, Alay Boon, Camiel J. Chhablani, Jay J Ophthalmic Vis Res Original Article PURPOSE: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. METHODS: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). RESULTS: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. CONCLUSION: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6504723/ /pubmed/31114653 http://dx.doi.org/10.4103/jovr.jovr_152_17 Text en Copyright: © 2019 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Hanumunthadu, Daren van Dijk, Elon H. C. Dumpala, Sunila Rajesh, Bindu Jabeen, Ayesha Jabeen, Asiya Ansari, Momin Mehta, Pooja Shah, Shilpi Sarvaiya, Chintan Meyerle, Catherine Wu, Lihteh Banker, Alay Boon, Camiel J. Chhablani, Jay Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy |
title | Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy |
title_full | Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy |
title_fullStr | Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy |
title_full_unstemmed | Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy |
title_short | Evaluation of Choroidal Layer Thickness in Central Serous Chorioretinopathy |
title_sort | evaluation of choroidal layer thickness in central serous chorioretinopathy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504723/ https://www.ncbi.nlm.nih.gov/pubmed/31114653 http://dx.doi.org/10.4103/jovr.jovr_152_17 |
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