A CRACker of an adaptor connects dynein-mediated transport to calcium signaling

Many different adaptor proteins activate the processivity of dynein–dynactin complexes and determine the specific cargo for retrograde transport by binding cargo receptors such as Rab GTP-binding (G) proteins. In this issue, Wang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806097) ide...

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Detalles Bibliográficos
Autores principales: Sharma, Mahak, Dwivedi, Devashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504887/
https://www.ncbi.nlm.nih.gov/pubmed/31010854
http://dx.doi.org/10.1083/jcb.201904069
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author Sharma, Mahak
Dwivedi, Devashish
author_facet Sharma, Mahak
Dwivedi, Devashish
author_sort Sharma, Mahak
collection PubMed
description Many different adaptor proteins activate the processivity of dynein–dynactin complexes and determine the specific cargo for retrograde transport by binding cargo receptors such as Rab GTP-binding (G) proteins. In this issue, Wang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806097) identify two GTPases that can function directly as dynein adaptors during endocytosis and are regulated by calcium.
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spelling pubmed-65048872019-11-06 A CRACker of an adaptor connects dynein-mediated transport to calcium signaling Sharma, Mahak Dwivedi, Devashish J Cell Biol Commentaries Many different adaptor proteins activate the processivity of dynein–dynactin complexes and determine the specific cargo for retrograde transport by binding cargo receptors such as Rab GTP-binding (G) proteins. In this issue, Wang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806097) identify two GTPases that can function directly as dynein adaptors during endocytosis and are regulated by calcium. Rockefeller University Press 2019-05-06 2019-04-22 /pmc/articles/PMC6504887/ /pubmed/31010854 http://dx.doi.org/10.1083/jcb.201904069 Text en © 2019 Sharma and Dwivedi http://www.rupress.org/terms/http://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Sharma, Mahak
Dwivedi, Devashish
A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
title A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
title_full A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
title_fullStr A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
title_full_unstemmed A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
title_short A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
title_sort cracker of an adaptor connects dynein-mediated transport to calcium signaling
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504887/
https://www.ncbi.nlm.nih.gov/pubmed/31010854
http://dx.doi.org/10.1083/jcb.201904069
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