Cargando…
CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic
Cytoplasmic dynein is a minus end–directed microtubule motor that transports intracellular cargoes. Transport is initiated by coiled-coil adaptors that (a) join dynein and its cofactor dynactin into a motile complex and (b) interact with a cargo-bound receptor, which is frequently a Rab GTPase on an...
Autores principales: | Wang, Yuxiao, Huynh, Walter, Skokan, Taylor D., Lu, Wen, Weiss, Arthur, Vale, Ronald D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504896/ https://www.ncbi.nlm.nih.gov/pubmed/30814157 http://dx.doi.org/10.1083/jcb.201806097 |
Ejemplares similares
-
Assembly and activation of dynein–dynactin by the cargo adaptor protein Hook3
por: Schroeder, Courtney M., et al.
Publicado: (2016) -
PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors
por: Budzinska, Marta I., et al.
Publicado: (2020) -
Endocytic Adaptors in Cardiovascular Disease
por: Cui, Kui, et al.
Publicado: (2020) -
A CRACker of an adaptor connects dynein-mediated transport to calcium signaling
por: Sharma, Mahak, et al.
Publicado: (2019) -
Disease-associated mutations in human BICD2 hyperactivate motility of dynein–dynactin
por: Huynh, Walter, et al.
Publicado: (2017)