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CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic

Cytoplasmic dynein is a minus end–directed microtubule motor that transports intracellular cargoes. Transport is initiated by coiled-coil adaptors that (a) join dynein and its cofactor dynactin into a motile complex and (b) interact with a cargo-bound receptor, which is frequently a Rab GTPase on an...

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Detalles Bibliográficos
Autores principales: Wang, Yuxiao, Huynh, Walter, Skokan, Taylor D., Lu, Wen, Weiss, Arthur, Vale, Ronald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504896/
https://www.ncbi.nlm.nih.gov/pubmed/30814157
http://dx.doi.org/10.1083/jcb.201806097

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