Utilizing a Simple Method for Stoichiometric Protein Labeling to Quantify Antibody Blockade

Ligand binding assays routinely employ fluorescently-labeled protein ligands to quantify the extent of binding. These ligands are commonly generated through chemical modification of accessible lysine residues, which often results in heterogeneous populations exhibiting variable binding properties. T...

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Detalles Bibliográficos
Autores principales: Friedman Ohana, Rachel, Hurst, Robin, Rosenblatt, Mike, Levin, Sergiy, Machleidt, Thomas, Kirkland, Thomas A., Encell, Lance P., Robers, Matthew B., Wood, Keith V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504924/
https://www.ncbi.nlm.nih.gov/pubmed/31065015
http://dx.doi.org/10.1038/s41598-019-43469-z

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