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Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report

BACKGROUND: Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. CASE PRESENTATIO...

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Autores principales: Garcia Casallas, Julio Cesar, Robayo-Amortegui, H., Corredor-Rozo, Z., Carrasco-Márquez, A. M., Escobar-Perez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505100/
https://www.ncbi.nlm.nih.gov/pubmed/31064407
http://dx.doi.org/10.1186/s13256-019-2062-3
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author Garcia Casallas, Julio Cesar
Robayo-Amortegui, H.
Corredor-Rozo, Z.
Carrasco-Márquez, A. M.
Escobar-Perez, Javier
author_facet Garcia Casallas, Julio Cesar
Robayo-Amortegui, H.
Corredor-Rozo, Z.
Carrasco-Márquez, A. M.
Escobar-Perez, Javier
author_sort Garcia Casallas, Julio Cesar
collection PubMed
description BACKGROUND: Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. CASE PRESENTATION: We report a case of a 64-year-old mestizo man hospitalized in an intensive care unit of a health institution in Colombia with identification and clinical and molecular typing of a colistin- and carbapenem-resistant A. baumannii isolate with mechanisms of resistance to colistin not previously reported, causing bacteremia. CONCLUSIONS: We have identified a strain of A. baumannii with mechanisms of resistance to colistin not previously reported in a patient with bacteremia who required treatment with multiple antibiotic schemes and had an adequate response.
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spelling pubmed-65051002019-05-10 Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report Garcia Casallas, Julio Cesar Robayo-Amortegui, H. Corredor-Rozo, Z. Carrasco-Márquez, A. M. Escobar-Perez, Javier J Med Case Rep Case Report BACKGROUND: Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. CASE PRESENTATION: We report a case of a 64-year-old mestizo man hospitalized in an intensive care unit of a health institution in Colombia with identification and clinical and molecular typing of a colistin- and carbapenem-resistant A. baumannii isolate with mechanisms of resistance to colistin not previously reported, causing bacteremia. CONCLUSIONS: We have identified a strain of A. baumannii with mechanisms of resistance to colistin not previously reported in a patient with bacteremia who required treatment with multiple antibiotic schemes and had an adequate response. BioMed Central 2019-05-08 /pmc/articles/PMC6505100/ /pubmed/31064407 http://dx.doi.org/10.1186/s13256-019-2062-3 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Garcia Casallas, Julio Cesar
Robayo-Amortegui, H.
Corredor-Rozo, Z.
Carrasco-Márquez, A. M.
Escobar-Perez, Javier
Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report
title Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report
title_full Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report
title_fullStr Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report
title_full_unstemmed Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report
title_short Bacteremia by colistin-resistant Acinetobacter baumannii isolate: a case report
title_sort bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505100/
https://www.ncbi.nlm.nih.gov/pubmed/31064407
http://dx.doi.org/10.1186/s13256-019-2062-3
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