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Determinants of QTL Mapping Power in the Realized Collaborative Cross

The Collaborative Cross (CC) is a mouse genetic reference population whose range of applications includes quantitative trait loci (QTL) mapping. The design of a CC QTL mapping study involves multiple decisions, including which and how many strains to use, and how many replicates per strain to phenot...

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Detalles Bibliográficos
Autores principales: Keele, Gregory R., Crouse, Wesley L., Kelada, Samir N. P., Valdar, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505132/
https://www.ncbi.nlm.nih.gov/pubmed/30914424
http://dx.doi.org/10.1534/g3.119.400194