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Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing

The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven burdensome, so the genomic location of most trans...

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Detalles Bibliográficos
Autores principales: Nicholls, Peter K., Bellott, Daniel W., Cho, Ting-Jan, Pyntikova, Tatyana, Page, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505145/
https://www.ncbi.nlm.nih.gov/pubmed/30837263
http://dx.doi.org/10.1534/g3.119.300582

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