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Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing
The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven burdensome, so the genomic location of most trans...
Autores principales: | Nicholls, Peter K., Bellott, Daniel W., Cho, Ting-Jan, Pyntikova, Tatyana, Page, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505145/ https://www.ncbi.nlm.nih.gov/pubmed/30837263 http://dx.doi.org/10.1534/g3.119.300582 |
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