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BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature
BACKGROUND: Hereditary colon cancer is characterized by the inheritance of an abnormal gene mutation which predisposes to malignancy. Recent advances in genomic medicine have identified mutations in “novel” genes as conferring an increased risk of colorectal cancer. Mutations in the BRIP1 gene (BRCA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505212/ https://www.ncbi.nlm.nih.gov/pubmed/31064327 http://dx.doi.org/10.1186/s12881-019-0812-0 |